Fig. 3From: MRI detection of the malignant transformation of stem cells through reporter gene expression driven by a tumor-specific promoterCell proliferation and invasion before and after malignant transformation. Cell proliferation was significantly faster in the MTMSC, MTMSC-PEG3-FTH1, and MTMSC-CMV-FTH1 groups than in the MSC, MSC-PEG3-FTH1, and MSC-CMV-FTH1 groups, respectively, beginning on the 3rd day after the cells were seeded (a). The number of cells that migrated though the membrane was notably larger in the MTMSC, MTMSC-PEG3-FTH1, and MTMSC-CMV-FTH1 groups than in the MSC, MSC-PEG3-FTH1, and MSC-CMV-FTH1 groups, respectively (b). There were significant differences in the cell invasion ratio between the corresponding pre- and post-malignant transformation groups (c)Back to article page