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Fig. 1 | Stem Cell Research & Therapy

Fig. 1

From: Induced pluripotent stem cell-derived mesenchymal stem cells deliver exogenous miR-105-5p via small extracellular vesicles to rejuvenate senescent nucleus pulposus cells and attenuate intervertebral disc degeneration

Fig. 1

Characterization of iMSC and sEVs. a Flow cytometric analyses of phenotypic markers of iMSC. iMSCs expressed CD29, CD44, and CD73 and were negative for CD34, CD45, and HLA-DR. b Western blotting analysis indicated that sEVs expressed sEV markers, such as CD9, CD63, and TSG101, and were negative for GM130 and Actin. c Morphology of sEVs under TEM. Scale bar, 200 nm. d Particle size distribution of sEVs measured by NTA

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