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Fig. 10 | Stem Cell Research & Therapy

Fig. 10

From: Mesenchymal stem cell-derived microvesicles improve intestinal barrier function by restoring mitochondrial dynamic balance in sepsis rats

Fig. 10

The schematic diagram for the mechanism of the therapeutic effect of MMVs on intestinal barrier function after sepsis. MMVs delivered mfn2, PGC-1α, and functional mitochondria to intestinal epithelial cells and synergistically restored the mitochondrial dynamic balance by promoting mitochondrial fusion and biogenesis, and subsequently improved mitochondrial oxidative phosphorylation and metabolism, thereby improving the intestinal barrier function

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Stem Cell Research & Therapy

ISSN: 1757-6512