Skip to main content
Fig. 3 | Stem Cell Research & Therapy

Fig. 3

From: Mesenchymal stem cell-derived microvesicles improve intestinal barrier function by restoring mitochondrial dynamic balance in sepsis rats

Fig. 3

MMVs improved the survival rate of sepsis rats and the function of IEC-6. a, b Animal survival curve and survival time (n=16). c Effect of MMVs on TEER of IEC-6 (n=5). d Effect of MMVs on BSA leakage of IEC-6 (n=6). e Effect of MMVs on CCK8 proliferation assay of IEC-6 (n=6). f The relative expression of PCNA in IEC-6 treated by MMVs. β-actin was used as the internal reference (n=5). g Representative microphotographs of scratch migration assay and the scratched area of IEC-6 treated by MMVs. The scale bar represents 100μm. h Representative IF microphotographs of ZO-1 in IEC-6 treated by MMVs. The scale bar represents 20μm. i Representative microphotographs of the endocytosis of PKH-26-labeled MMVs in IEC-6. The scale bar represents 10μm. Ctl, normal control group; LPS, LPS-stimulated group; CMV, CMV-treated group; MMV, MMV-treated group. **P < 0.01

Back to article page

Stem Cell Research & Therapy

ISSN: 1757-6512