Skip to main content
Fig. 6. | Stem Cell Research & Therapy

Fig. 6.

From: Development, characterization, and hematopoietic differentiation of Griscelli syndrome type 2 induced pluripotent stem cells

Fig. 6.

Engraftment of human iPSC-derived HSCs in immune-deficient mice. Immune deficient Rag2−/− mice were pre-treated with busulfan and transplanted with 5 × 105–106 cells obtained from human iPSC-derived HSC cultures per mouse (n=15). a Peripheral blood samples were collected at 1–6 months after transplant and assessed for the presence of human hematopoietic cells. b Groups of mice were sacrificed at month 3 and 6 to assess the presence of human hematopoietic cells in the spleen (SPL) and bone marrow (BM) tissue

Back to article page