Baseline characteristics* | Mild AKI# (n = 20) | Severe AKI# (n = 15) | p value†|
---|---|---|---|
Demographics | |||
 Age, years | 54.0 (26.3) | 66.7 (12.4) | 0.013c |
 Male | 12 (60.0) | 11 (73.3) | 0.64a |
 Smoking | 3 (15.0) | 3 (20.0) | 1.00b |
 Diabetes | 3 (15.0) | 4 (26.7) | 0.43b |
 Hypertension | 11 (55.0) | 9 (60.0) | 1.00b |
Laboratory and histological data | |||
 Serum creatinine, mg/dL | 0.90 (0.47) | 3.56 (4.01) | < 0.001c |
 Glomerular filtration rate, mL/min | 89.2 (43.7) | 16.7 (25.7) | < 0.001c |
 Interstitial fibrosis, % | 10 (10) | 30 (10) | < 0.001c |
 Interstitial inflammation, % | 10 (7.5) | 30 (20) | < 0.001c |
 LC3B mRNA levels, TPM | 104 (25.1) | 120 (19.9) | 0.006c |