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Table 1 Baseline characteristics of patients with mild or severe ischemic acute kidney injury

From: Hypoxic mesenchymal stem cells ameliorate acute kidney ischemia-reperfusion injury via enhancing renal tubular autophagy

Baseline characteristics* Mild AKI# (n = 20) Severe AKI# (n = 15) p value
Demographics
 Age, years 54.0 (26.3) 66.7 (12.4) 0.013c
 Male 12 (60.0) 11 (73.3) 0.64a
 Smoking 3 (15.0) 3 (20.0) 1.00b
 Diabetes 3 (15.0) 4 (26.7) 0.43b
 Hypertension 11 (55.0) 9 (60.0) 1.00b
Laboratory and histological data
 Serum creatinine, mg/dL 0.90 (0.47) 3.56 (4.01) < 0.001c
 Glomerular filtration rate, mL/min 89.2 (43.7) 16.7 (25.7) < 0.001c
 Interstitial fibrosis, % 10 (10) 30 (10) < 0.001c
 Interstitial inflammation, % 10 (7.5) 30 (20) < 0.001c
 LC3B mRNA levels, TPM 104 (25.1) 120 (19.9) 0.006c
  1. *Values for categorical and continuous variables are expressed as numbers (percentages) and median (interquartile range), respectively
  2. #Patients were stratified into mild (injured tubules < 50%) or severe (injured tubules ≥ 50%) ischemic acute kidney injury according to the percentage of injured tubules in the pathology of renal biopsy specimens
  3. Between-group comparisons by the aPearson’s χ2 test, bFisher’s exact test, or cWilcoxon rank sum test where appropriate