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Table 1 Baseline characteristics of patients with mild or severe ischemic acute kidney injury

From: Hypoxic mesenchymal stem cells ameliorate acute kidney ischemia-reperfusion injury via enhancing renal tubular autophagy

Baseline characteristics*

Mild AKI# (n = 20)

Severe AKI# (n = 15)

p value†

Demographics

 Age, years

54.0 (26.3)

66.7 (12.4)

0.013c

 Male

12 (60.0)

11 (73.3)

0.64a

 Smoking

3 (15.0)

3 (20.0)

1.00b

 Diabetes

3 (15.0)

4 (26.7)

0.43b

 Hypertension

11 (55.0)

9 (60.0)

1.00b

Laboratory and histological data

 Serum creatinine, mg/dL

0.90 (0.47)

3.56 (4.01)

< 0.001c

 Glomerular filtration rate, mL/min

89.2 (43.7)

16.7 (25.7)

< 0.001c

 Interstitial fibrosis, %

10 (10)

30 (10)

< 0.001c

 Interstitial inflammation, %

10 (7.5)

30 (20)

< 0.001c

 LC3B mRNA levels, TPM

104 (25.1)

120 (19.9)

0.006c

  1. *Values for categorical and continuous variables are expressed as numbers (percentages) and median (interquartile range), respectively
  2. #Patients were stratified into mild (injured tubules < 50%) or severe (injured tubules ≥ 50%) ischemic acute kidney injury according to the percentage of injured tubules in the pathology of renal biopsy specimens
  3. †Between-group comparisons by the aPearson’s χ2 test, bFisher’s exact test, or cWilcoxon rank sum test where appropriate