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Fig. 8 | Stem Cell Research & Therapy

Fig. 8

From: Senescence of donor cells impairs fat graft regeneration by suppressing adipogenesis and increasing expression of senescence-associated secretory phenotype factors

Fig. 8

Donor age negatively impacts differentiation of AD-MSCs. a, b Perilipin staining and quantification of the perilipin-positive area in old and young AD-MSCs. c Illustration of the co-culture model. d MILLIPLEX® MAP assays measuring the levels of 18 cytokines/chemokines in conditioned media of old and young adipose tissue. e, f Perilipin staining and quantification of the perilipin-positive area in old AD-MSCs treated with the culture supernatant of old or young adipose tissue. **p < 0.01 and *p < 0.05 vs. data from different groups. Data are presented as the mean ± SEM of three independent experiments

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