Fig. 2From: Rspo3 regulates the abnormal differentiation of small intestinal epithelial cells in diabetic stateThe expression of Rspo3 in the IECs in DM. a RT-qPCR analysis showed the mRNA expression of Rspos in the IECs of the db/db mice and the db/+ mice. b, c Rspo3 protein levels were also significantly upregulated in the IECs of the db/db mice. d, e Immunohistochemistry showed that Rspo3 expression was localized around the crypt base. Scale bar, 50 μm; mean ± SD, n = 6; *P < 0.05Back to article page