Fig. 3
From: Rspo3 regulates the abnormal differentiation of small intestinal epithelial cells in diabetic state
Abnormal differentiation of IECs in the DM state is associated with overexpression of Rspo3. a The knockdown efficiencies after transfection of siRNAs in vitro. b The mRNA expression of SI, Tff3, Lyz1, and ChgA after si-Rspo3 transfection into the IECs of the db/db mice. c, d Western blot analysis showed the protein expression of SI, Tff3, Lyz1, and ChgA in the si-Rspo3-treated db/db mice. e, f The numbers of SI-, Tff3-, Lyz1-, and ChgA-positive cells in the si-Rspo3-administered db/db mice. Scale bar, 50 μm; mean ± SD, n = 6; *P < 0.05 vs db/+-NS