The whole profiling and competing endogenous RNA network analyses of noncoding RNAs in adipose-derived stem cells from diabetic, old, and young patients

Table 1 Basic characteristics of different groups included in the study

Variables	Young donors	Old donors	Diabetic donors	p value (Y/O)	p value (O/D)
Number	14	15	8	NA	NA
Age Range	8.14 ± 2.93 [3, 12]	54.20 ± 3.95 [49, 61]	56.88 ± 8.01 [48, 71]	< 0.001*** NA	0.29 NA
BMI	19.13 ± 3.76	22.02 ± 2.72	23.71 ± 2.33	0.04*	0.21
SBP	115 ± 12.61	126.54 ± 8.64	130.42 ± 20.19	0.03*	0.55
DBP	75 ± 7.98	80.00 ± 6.40	82.71 ± 12.41	0.14	0.52
FBG	4.87 ± 0.37	5.00 ± 0.72	9.02 ± 2.52	0.60	< 0.001***
HbA1c	NA	NA	10.21 ± 2.75	NA	NA
TG	1.15 ± 0.52	1.53 ± 0.85	1.35 ± 0.66	0.29	0.59
TC	3.68 ± 0.65	4.44 ± 0.85	4.21 ± 1.31	0.20	0.71
HDL	1.23 ± 0.22	1.19 ± 0.33	0.89 ± 0.19	0.83	0.13
LDL	1.98 ± 0.67	2.65 ± 0.75	2.71 ± 1.33	0.01*	0.92
Cr	37.00 ± 5.42	51.08 ± 16.98	74.20 ± 11.46	0.02*	0.009**
BUN	3.89 ± 1.21	4.13 ± 0.91	4.84 ± 1.28	0.40	0.19

Diabetic donors: donors with type 2 diabetes; range: minimum age, maximum age; BMI (kg/m²): body mass index; SBP (mm Hg): systolic blood pressure; DBP (mm Hg): diastolic blood pressure; FBG (mmol/L): fasting blood glucose; HbA1c (%): glycated hemoglobin; TG (mmol/L): triglyceride; TC (mmol/L): total cholesterol; HDL-C (mmol/L): high-density lipoprotein cholesterol; LDL-C (mmol/L): low-density lipoprotein cholesterol; Cr (μmol/L): creatinine; BUN (mmol/L): blood urea nitrogen; NA: not available. Data are expressed as mean ± SD and were statistically analyzed by the un-paired Student’s t test. *p< 0.05, **p< 0.01, ***p< 0.001

ISSN: 1757-6512