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Fig. 2 | Stem Cell Research & Therapy

Fig. 2

From: Exosomes from miRNA-378-modified adipose-derived stem cells prevent glucocorticoid-induced osteonecrosis of the femoral head by enhancing angiogenesis and osteogenesis via targeting miR-378 negatively regulated suppressor of fused (Sufu)

Fig. 2

Effects of miR-378-ASCs-Exos on cell migration, proliferation, and angiogenetic capacity. a Cell migration ability measured by Transwell assays. b Tube formation capability detected in HUVECs endothelial cells stimulated with 5 μg/mL ASCs-Exos or ASCs-miR-378-Exos 24 h. c Western blot and quantification of ANG-1, VEGF expression in HUVECs. d Cell proliferation of HUVECs treated with DEX with or without miR-378-ASCs-Exos, as evaluated by CCK-8 analysis. *P < 0.05, **P < 0.01 compared with the DEX group. #P < 0.05, ##P < 0.01

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