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Fig. 2 | Stem Cell Research & Therapy

Fig. 2

From: IL-1β pre-stimulation enhances the therapeutic effects of endometrial regenerative cells on experimental colitis

Fig. 2

IL-1β-primed ERCs alleviate the symptoms of DSS-induced colitis. A Representative pictures showing bloody stool were taken on the 10th day after DSS induction. The mice in the IL-1β-primed ERC group were in the best condition than that in other groups. Body weight changes (B) and Disease Activity Index (DAI) score (C) of each group of mice were recorded daily. In the IL-1β-primed ERC group, the weight loss and DAI score were shown lesser than other groups. D, E The length of the colon in each group was measured and analyzed on the 10th day (n = 6). F Photograph (× 200, H&E staining) of representative histological sections of mouse colons in each group. Arrows indicated the inflammatory cell infiltration. G Histopathological scores were calculated according to the scoring system directed by Singh et al. [31] to assess the colonic injury quantitatively. Data were presented as mean ± standard deviation (SD) (*p < 0.05, **p < 0.01, ***p < 0.001). Statistical analysis was calculated by using one-way analysis of variance (ANOVA) followed by the least significant difference (LSD) test

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