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Fig. 8 | Stem Cell Research & Therapy

Fig. 8

From: Methylsulfonylmethane enhances MSC chondrogenic commitment and promotes pre-osteoblasts formation

Fig. 8

MSM affects miR146b expression and ERK signaling. MiR 146b expression was reduced in both fin and scale treated with MSM (A). Increased ERK levels and reduced pERK levels and pERK/ERK ratio were observed in both fin and scale of MSM-treated zebrafish; a: control fin; b: treated fin; c: control scale; d: treated scale (B). A schematic graphic showing as MSM promotes chondroblast progenitors and pre-osteoblast maturation by reducing ERK phosphorylation (C).

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