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Fig. 2 | Stem Cell Research & Therapy

Fig. 2

From: Photoactivation of TGFβ/SMAD signaling pathway ameliorates adult hippocampal neurogenesis in Alzheimer’s disease model

Fig. 2

PBMT improves spatial learning/memory of APP/PS1 mice in the Y maze and Morris water maze (MWM). a Spontaneous alternating data statistics after PBMT, (n = 8 mouse at 7 months of age for each group after PBMT). b–d Duration of novel arm visits data statistics (b), distance traveled of novel arm data statistics (c) and the number of novel arm entries data statistics (d) after PBMT (n = 8 mouse at 7 months of age for each group after PBMT). e The escape latency during the 5 days of the training phase in mice. f Representative swimming traces of the four groups of mice exhibited during the MWM test. g, h The number of passes across the escape platform (g) and the percentage of time spent in the target quadrant (h) during the MWM test, (n = 6 mouse at 7 months of age for each group after PBMT). All data were detected by the Y maze test or MWM test. All quantifications are presented as mean ± SEM and were analyzed by one-way ANOVA test; *p < 0.05, #p < 0.05 versus indicated group

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