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Fig. 2 | Stem Cell Research & Therapy

Fig. 2

From: Epidermal stem cells maintain stemness via a biomimetic micro/nanofiber scaffold that promotes wound healing by activating the Notch signaling pathway

Fig. 2

PCL+CA micro/nanofiber scaffold can maintain the stemness of EpSCs through inhibition of the Notch signaling pathway. a Representative western blot images and densitometric analysis results showing the relative expression levels of cyclin D1/E1 in EpSCs cultured in 2D dishes and scaffolds. b Representative western blot images and results of densitometric analysis showed relative expression levels of ESC differentiation-related proteins cytokeratin 10/14/19 in EpSCs cultured in 2D dishes and scaffolds. c Cytokeratin 19 (red) and PCNA (green) staining of cells seeded in IV collagen-coated culture dishes and in scaffolds. Scale bar = 50 μm. d Integrin ɑ6 (red) and PCNA (green) staining of cells seeded in IV collagen-coated culture dishes and in scaffolds. Scale bar = 20 μm. *P<0.05, **P<0.01, ***P<0.001, ****P<0.0001 vs the control group

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Stem Cell Research & Therapy

ISSN: 1757-6512