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Fig. 1 | Stem Cell Research & Therapy

Fig. 1

From: The stemness of hepatocytes is maintained by high levels of lipopolysaccharide via YAP1 activation

Fig. 1

Correlation between the location of hepatic stem cells and the concentration of LPS in the liver. a Representative Sox9 (red) and GS (green) staining of the liver. CV, central vein; PV, portal vein. Nuclei were counterstained with DAPI (blue). b Representative IHC staining of serial liver sections for Sox9 and GS. c The concentration of LPS in the mouse portal vein (PV) and inferior vena cava (IVC). d Western blot assay of Sox9 in mice from the control and antibiotic groups. e Double staining of the liver for Sox9 and TLR4. f Left: Representative IHC staining of the liver for Sox9 in WT and TLR4-/- mice; right: quantification of Sox9+ cell numbers. Scale bars, 100 μm. The data are expressed as the mean ± SD. *P < 0.05, ***P < 0.001

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