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Fig. 7 | Stem Cell Research & Therapy

Fig. 7

From: Human endometrium-derived stem cell improves cardiac function after myocardial ischemic injury by enhancing angiogenesis and myocardial metabolism

Fig. 7

In vivo implantation of hEMSCs enhanced the expression of pro-angiogenic cytokines after MI. The level of mRNA expression for VEGF (a), angiopoietin 1 (ANG1, b), and angiopoietin 2 (ANG2, c) was measured in the infarcted heart tissue of nude rats at 3 days after cell transplantation by real-time qPCR. Individual values were normalized to glyceraldehyde 3-phosphate dehydrogenase (GAPDH). Representative Western blot images and quantification of VEGFA, ANG1 and ANG2 (d), Fms-like tyrosine kinase 1 (FLT-1) and TIE2 (e), transforming growth factor β2 and FGF9 (f) protein levels in the infarcted heart tissue of nude rats at 3 days after cell transplantation. Data are expressed as mean ± SEM. n = 3 or 4/group for all assays

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Stem Cell Research & Therapy

ISSN: 1757-6512