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Fig. 3 | Stem Cell Research & Therapy

Fig. 3

From: Hypoproliferative human neural progenitor cell xenografts survived extendedly in the brain of immunocompetent rats

Fig. 3

The massive death of human NPC grafts is due to immune rejection in the vast majority of cases. A The reoccupation of the rejected graft area by the host cells with strong IBA1 expression. Scale bar, 50 μm. B The infiltration of the rejected grafts with CD3+ lymphocytes which are completely absent in non-rejected human grafts. Scale bar, 50 μm. C Heavy host IgG deposition within the rejected grafts but not in the non-rejecting brain. Scale bar, 50 μm

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