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Fig. 4 | Stem Cell Research & Therapy

Fig. 4

From: Mesenchymal stem cells ameliorate renal fibrosis by galectin-3/Akt/GSK3β/Snail signaling pathway in adenine-induced nephropathy rat

Fig. 4

MSCs treatment reduced kidney injury scores and collagen components of extracellular matrix in the tubulointerstitium by histopathology analysis of renal tissues from adenine-induced rats. A Hematoxylin-eosin (H&E) staining. B Masson staining. C Sirius Red staining. Representative histochemical staining images of Sirius Red staining and Masson trichrome staining images were taken in kidney sections at 5 days post-MSCs treatment (scale bar, 100 μm). The statistical graph shows the area(sum) of the positive area (n = 6–8 in each group) by the Image Pro Plus 6.0 software. N = 5 (per group), data are presented as mean ± SD, and analyzed by one-way ANOVA followed by Bonferroni post hoc testing. *P < 0.05, vs. control group, #P < 0.05, vs. adenine group

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