Fig. 8

Global protein expression patterns in adenine-induced rat kidneys. A Volcano plots showing the distribution of significance and fold change of identified proteins in the adenine+MSCs group/adenine group comparison. All proteins were plotted with log₂ (fold change) on the x-axis and log₁₀ (p-value) on the y-axis. Vertical dotted lines mark a fold change of ± 120% and the horizontal dotted line marks P = 0.05. B K-means clustering representation of total 40 different expression proteins (DEPs). The magnitude of the percentage is represented by a color scale (top right) going from low (red) to high (blue). C GO annotation and functional classification of DEPs: Gene ontology terms for subcellular location distribution, molecular functions, and biological process