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Fig. 5 | Stem Cell Research & Therapy

Fig. 5

From: Individual heterogeneity screened umbilical cord-derived mesenchymal stromal cells with high Treg promotion demonstrate improved recovery of mouse liver fibrosis

Fig. 5

HUCMSCs inhibited the differentiations of CD4+ T cells into Th1 and Th17 subsets, promoted the maturation of Tregs subpopulation in PBMCs induced by IL-2. There was remarkable individual heterogeneity in immune regulation among 12 test HUCMSCs, and the same cell strain also had a different capability in every aspect of immune regulation (*p < 0.05, ***p < 0.001)

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