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Fig. 7 | Stem Cell Research & Therapy

Fig. 7

From: Exosome-transported circRNA_0001236 enhances chondrogenesis and suppress cartilage degradation via the miR-3677-3p/Sox9 axis

Fig. 7

MSC-circ_0001236-Exos inhibits cartilage degradation in the DMM mouse model. a Safranin O and Fast Green staining, in situ hybridization of circ_0001236, and immunohistochemistry analysis of Col2a1, Sox9, and MMP13 are shown in the sections of the knee joints (n = 5 per group) from mice (scale bar, 50 μm). b OARSI scores of the knee joints of DMM mice of the five cohorts. Fold change of positive cell rates of Col2a1 (c), Sox9 (d), MMP13 (e), and circ_0001236 (f). *P < 0.05, **P < 0.01, ***P < 0.001

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