Fig. 3

In vitro analysis of protein expressions of oxidative stress. A1, A2 Protein expression of NOX-1, * vs. other groups with different symbols (†, ‡), p< 0.001. B1, B2 Protein expression of NOX-2, * vs. other groups with different symbols (†, ‡), p< 0.001. C1, C2 Protein expression of cyclophilin D (cyc-D), * vs. other groups with different symbols (†, ‡), p< 0.001. D1, D₂ Protein expression of and dynamin-related protein 1 (DRP1), * vs. other groups with different symbols (†, ‡), p< 0.001. E1, E2 Protein expression of ratio of LC3B-II to LC3B-I, * vs. other groups with different symbols (†, ‡), p< 0.001. F1, F2 Protein expression of cytosolic cytochrome C (cyt-cytC), * vs. other groups with different symbols (†, ‡), p< 0.001 (Actin). G1, G2 Protein expression of mitochondrial cytochrome C (mit-cytC), * vs. other groups with different symbols (†, ‡), p< 0.001. All statistical analyses were performed by one-way ANOVA, followed by Bonferroni multiple comparison post hoc test (n=3). Symbols (*, †, ‡) indicate significance (at 0.05 level). G1= iPS-MSC; G2 = iPS-MSC^dOex-mIRs; G3 = iPS-MSC + H₂O₂/100uM; G4 = iPS-MSC^dOex-mIRs + H₂O₂/100uM