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Fig. 3 | Stem Cell Research & Therapy

Fig. 3

From: Bone marrow-derived mesenchymal stem/stromal cells in patients with acute myeloid leukemia reveal transcriptome alterations and deficiency in cellular vitality

Fig. 3

Gene expression profiling of HD-MSCs and AML-MSCs. a, b The distributions of gene expression in HD-MSCs (HD-1, HD-2, HD-3) and AML-MSCs (AML-1, AML-2, AML-3) based on log2 (FPKM+1) (a) and -log2 (P value) (b), respectively. c Correlation analysis of AML-MSCs and HD-MSCs by HeatMap diagram. d Principal component analysis (PCA) of AML-MSCs and HD-MSCs. e, f Gene set enrichment analysis (GSEA) of differentially functional gene subsets in HD-MSCs (e) and AML-MSCs (f), respectively. g, h Gene ontology of upregulated genes (g) and downregulated genes (h) in AML-MSCs compared with HD-MSCs

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Stem Cell Research & Therapy

ISSN: 1757-6512