Fig. 3
From: Restoration of keratinocytic phenotypes in autonomous trisomy-rescued cells
Differentiating cells from T21-iPSCs and the rescued disomy (D21)-iPSCs shows proliferative capability for more than 160 days. The numbers of cells were recorded at each passage using an automated cell counter and population doublings were determined. The total number of population doublings (PDs) was calculated using the formula [log10 (total number of harvested cells/number of plated cells)]/log10 (2) from two or three independent experiments