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Fig. 1 | Stem Cell Research & Therapy

Fig. 1

From: Serum exosomes from young rats improve the reduced osteogenic differentiation of BMSCs in aged rats with osteoporosis after fatigue loading in vivo

Fig. 1

Bone mineral densities of aged osteoporotic rats with bone microdamage and bone microdamage after mechanical loading. A Experimental diagram of the induction of bone microdamage in aged osteoporotic rats. B BMD areas of the vertebral bodies of SD females before and after OVX as measured using DAX (pre-OVX (7 months old) and post-OVX (7 months old), n = 19; post-ovx (22 months old), n = 13). C Bone microdamage as observed using a fluorescence microscope (white arrow). Scale bar: 200 μm. D Microdamage parameters, including the cortical bone area, proportion of cortical bone area, microcrack length (Cr. Le), microcrack density (Cr. Dn), and microcrack surface density (Cr. S. Dn) (n = 4). The data are expressed as the mean ± SEM. *P < 0.05, **P < 0.01, ****P < 0.0001

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Stem Cell Research & Therapy

ISSN: 1757-6512