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Fig. 1 | Stem Cell Research & Therapy

Fig. 1

From: CD90low glioma-associated mesenchymal stromal/stem cells promote temozolomide resistance by activating FOXS1-mediated epithelial-mesenchymal transition in glioma cells

Fig. 1

Glioma cell line U87MG show increased TMZ resistance ability in gaMSC-conditioned media in vitro. A Morphology of U87MG in normal condition (mo.U87) and gaMSC-conditioned media (co.U87) (× 40, scale bar = 200 μm). B Proliferation curve of mo.U87 and co.U87 with different concentrations of TMZ (n ≥ 3, **P < 0.01, ****P < 0.0001). C Wound-healing assay of mo.U87 and co.U87 cells under TMZ treatment. n ≥ 3, *P < 0.05. D Apoptosis of mo.U87 and co.U87 cells under TMZ treatment. - no TMZ, + add TMZ (n ≥ 3, *P < 0.05, ****P < 0.0001)

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