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Fig. 6 | Stem Cell Research & Therapy

Fig. 6

From: CD90low glioma-associated mesenchymal stromal/stem cells promote temozolomide resistance by activating FOXS1-mediated epithelial-mesenchymal transition in glioma cells

Fig. 6

Glioma cells with different FOXS1 expression show activated EMT process and increased TMZ resistance ability in tumour-bearing mice. Tumour volume (A), EMT markers (B), Ki67-staining (C) and apoptosis assay (D) were investigated in tumour-bearing mice inoculated with control-U87/NC-U87/KD-U87/OE-U87 and treated with TMZ (× 400, scale bar = 250 μm, n = 3, *P < 0.05, **P < 0.01, ***P < 0.001, ****P < 0.0001)

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Stem Cell Research & Therapy

ISSN: 1757-6512