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Fig. 4 | Stem Cell Research & Therapy

Fig. 4

From: Mesenchymal stem cells alleviate idiopathic pneumonia syndrome by modulating T cell function through CCR2-CCL2 axis

Fig. 4

Prophylactic effect of MSCs on GVHD and lung pathological injury in IPS mice. MSCs were co-injected with bone marrow cells and spleen cells via the tail vein for prophylaxis of GVHD and lung injury in IPS mouse model. The effect of MSCs on a mouse survival, b weight changes, and c clinical scores of GVHD were shown. Mouse lung tissue specimens were collected for HE staining. d The pathological score of each group. e One of the representatives of pathological results in each group. f One of the representative results of CD3+ T cell infiltration observed by immunohistochemical staining. n=9, *P < 0.05; **P < 0.01; ***P < 0.001; n.s., no statistical difference

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Stem Cell Research & Therapy

ISSN: 1757-6512