Fig. 3

Temporal profiling of selected cytokines for individual patients based on dose groups (low, middle, and high). Blood was drawn from patients on week 4, immediately prior to the dental implant procedure on week 12 and during follow-up visits on weeks 16 and 24. Chemokine level was regressed over time using ordinary linear regression to estimate changes over time. Regression testing was done to estimate the profiles of Fractalkine (Fracktalk), interleukin-17A (IL-17A), fibroblast growth factor 2 (FGF2), eotaxin, macrophage-derived chemokine (MDC), and monocyte chemoattractant protein-1 (MCP-1). Results are given as concentration levels (pg/mL) on y-axis over time x-axis. Bolded red line represents β from generalized estimating equation