Skip to main content

Table 4 Cytokines and chemokines changes

From: Small blood stem cells for enhancing early osseointegration formation on dental implants: a human phase I safety study

Low dose Middle dose High dose
var avg_change p_value var avg_change p_value var avg_change p_value
EGF 12.94 0.082 EGF − 1.33 0.6061 EGF 16 0.1777
FGF2 − 0.83 0.7778 FGF2 5.18 0.0035* FGF2 3.14 0.0581
Eotaxin 4.92 0.1053 Eotaxin 2.76 0.0043* Eotaxin 4.72 0.3712
TGF_alph 0.14 0.4226 TGF_alph 0.21 0.4226 TGF_alph 0 1
G_CSF 0.64 0.4226 G_CSF 10.48 0.288 G_CSF 0.6 0.7915
Flt_3L 0 1 Flt_3L 0 1 Flt_3L 1.38 0.4226
GM_CSF − 0.5 0.4226 GM_CSF 1.01 0.1904 GM_CSF 0.01 0.99
Fractalk − 19.1 0.0104* Fractalk − 0.44 0.4226 Fractalk 8.77 0.4226
IFN_alph 0 1 IFN_alph 0.22 0.4226 IFN_alph 0.26 0.4226
IFN_gamm − 0.85 0.3704 IFN_gamm − 1.32 0.4114 IFN_gamm 1.49 0.4382
GRO 77.88 0.3749 GRO 47.98 0.2373 GRO − 2.21 0.9386
IL_10 0 1 IL_10 − 1.45 0 4802 IL_10 0 1
MCP_3 0 1 MCP_3 3.66 0.2609 MCP_3 0.86 0.4226
IL_12p40 0 1 IL_12p40 0 1 IL_12p40 0 1
MDC 22.33 0.3761 MDC 55.89 0.0446* MDC 5.01 0.8816
IL_12p7 0 0 1 IL_12p7 0 0.53 0.4226 IL_12p7 0 0.26 0.4226
IL_13 0 1 IL_13 − 0.37 0.8552 IL_13 1.06 0.4624
IL_15 0 1 IL_15 0.29 0.4226 IL_15 0.06 0.4226
sCD40L 1714.04 0.2155 sCD40L 488.89 0.2467 sCD40L 594.57 0.0859
IL_17A − 0.83 0.2321 IL_17A − 0.56 0.1837 IL_17A 0.17 0.8197
IL_1RA − 1.93 0.672 IL_1RA − 0.57 0.8492 IL_1RA 0.8 0.4226
IL_1alph 0 1 IL_1alph 0.68 0.9572 IL_1alph 7.64 0.4226
IL_9 0 1 IL_9 − 0.09 0.4226 IL_9 0.34 0.4226
IL_lbeta 0 1 IL_lbeta 0 1 IL_lbeta 0 1
IL_2 0 1 IL_2 − 0.22 0.4226 IL_2 0 1
IL_3 0 1 IL_3 0 1 IL_3 0 1
IL_4 6.48 0.315 IL_4 23.67 0.4287 IL_4 11.83 0.4226
IL_5 − 0.35 0.4226 IL_5 − 0.34 0.4226 IL_5 0.26 0.4226
IL_6 0 1 IL_6 2.2 0.3444 IL_6 1.16 0.4226
IL_7 − 0.48 0.3651 IL_7 1.54 0.1542 IL_7 − 0.86 0.5098
IL_8 0.7 0.2546 IL_8 1.8 0.0705 IL_8 0.77 0.556
IP_10 13.45 0.4772 IP_10 − 0.6 0.9709 IP_10 − 16.72 0.2174
MCP_1 21.64 0.0008* MCP_1 15.45 0.0039 MCP_1 12.5 0.5057
MIP_lalp 0.85 0.4452 MIP_lalp − 1.36 0.1323 MIP_lalp 3.11 0.3513
MIP_lbet 3.73 0.3903 MIP_lbet 9.02 0.0989 MIP_lbet 5.28 0.2209
TNF_alph 1.22 0.2699 TNF_alph − 0.74 0.0006 TNF_alph 4.87 0 4082
TNF_beta 0 1 TNF_beta 4.28 0.3584 TNF_beta 1.52 0.4226
VEGF − 3.67 0.651 VEGF 20.11 0.1275 VEGF 7.56 0.2767
  1. Abbreviatlons: var variable, avg average
  2. * indicates p < 0.05