Fig. 4

The effects of MSC injection on liver fat content and serum lipid profiles. A, B Representative images of Oil Red O-stained liver sections of the indicated groups. Scale bar = 50 μm. The red lipid staining were used for statistics. db/db mice were injected with human UC-MSCs, PU-MSCs, AD-MSCs, or PBS every 2 weeks for 6 weeks. MET, metformin. After the last injections, serum concentrations of C TC, D TG, E HDL-C, and F LDL-C in the indicated groups were measured. The results are expressed as the means ± S.E.M. n = 6 mice per group. ^*P<0.05, ^**P<0.01, ^***P<0.001 versus the vehicle group. One-way ANOVA