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Fig. 1 | Stem Cell Research & Therapy

Fig. 1

From: Stem cell therapies for autoimmune hepatitis

Fig. 1

Postulated immunomodulatory role of MSCs, modified MSCs, and their exosomes in an AIH animal model. AIH, autoimmune hepatitis; Th17, T helper 17 cells; IL, interleukin; CTL, cytotoxic CD8+ T lymphocyte; JAK, Janus kinase; STAT, signal transducer and activator of transcription; FASL, Fas ligand; IFN-γ, interferon-gamma; PD-L1, the ligand of PD-1 “programmed death-1”; TNF, tumor necrosis factor; NLRP3, nucleotide-binding domain-like receptor protein 3. The figure was created using the images from Servier Medical Art

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