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Fig. 2 | Stem Cell Research & Therapy

Fig. 2

From: Human umbilical cord mesenchymal stromal cells attenuate pulmonary fibrosis via regulatory T cell through interaction with macrophage

Fig. 2

hucMSC infusion promoted lung regeneration. A Day 7 after bleomycin treatment, lung sections were stained with antibodies against proSPC and Ki67. White arrowheads indicate proliferating alveolar type 2 cells. B The percentage of Ki67-positive alveolar type 2 cells (mean ± SD, n = 3 mice per group). C Flow cytometry analysis of EdU incorporation in alveolar type 2 cells in saline-treated mice lungs, bleomycin-treated mice lungs, and hucMSC-treated mice lungs on day 7 and day 14. D The percentage of EdU-positive alveolar type 2 cells (mean ± SD, n = 3 mice per group). E Flow cytometry analysis of EdU incorporation in lung fibroblast cells in saline-treated mice lungs, bleomycin-treated mice lungs, and hucMSC-treated mice lungs on day 7 and day 14. F The percentage of EdU-positive lung fibroblast cells (mean ± SD, n = 3 mice per group). *p < 0.05, **p < 0.01, n.s. no significant difference, Student’s t-test

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Stem Cell Research & Therapy

ISSN: 1757-6512