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Fig. 4 | Stem Cell Research & Therapy

Fig. 4

From: Human umbilical cord mesenchymal stromal cells attenuate pulmonary fibrosis via regulatory T cell through interaction with macrophage

Fig. 4

Single cell RNA sequencing revealed an interferon-sensitive macrophage population in hucMSCs infused lungs. A UMAP plot of macrophages from bleomycin- and hucMSC-treated mouse lungs. B, C The proportions of different macrophage clusters. D Heatmap of some differentially expressed genes between each macrophage cluster. E t-SNE visualization overlaid with the expression of Spp1, H2-Eb1, Rsad2, F13a1, Car4, and Nr4a1. F Violin plots of Rsad2, Isg15, Ifit1, Ifit2, Ifit3, Ifi204, Ifi205, and Irf7 expression in each macrophage cluster

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Stem Cell Research & Therapy

ISSN: 1757-6512