Fig. 3

hAECs reduce levels of hepatic leukocytes, neutrophil infiltration and myeloperoxidase production. Compared with normal mice, mice on the NASH diet only (FF) and mice treated with a double dose of hAECs (FFHD) had significantly more hepatic leukocytes (CD45+ cells) (a). Within the NASH diet groups, both FFHS and FFHD mice had significantly lower levels of hepatic leukocytes compared to untreated FF mice (a). Within the mice treated with hAECs, FFHS mice had significantly fewer hepatic leukocytes compared to FFHD mice (a). Compared with normal mice, mice on the NASH diet, had significantly more neutrophils (NIMP-R14+ cells) (b). Within the NASH diet groups, FFHS and FFHD mice had significantly lower levels of neutrophils compared to untreated FF mice (b). Compared with normal mice, mice on the NASH diet, (FF, FFHS and FFHD) had significantly greater levels of MPO activity (MPO+ cells) (c). Within the NASH diet groups, FFHS and FFHD mice had significantly lower levels of MPO activity compared to untreated FF mice (c). Magnification: × 10, scale bar = 50 μm; red box indicating selected area at × 20 magnification. **P < 0.01, ***P < 0.001, ****P < 0.0001. MPO, myeloperoxidase