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Fig. 5 | Stem Cell Research & Therapy

Fig. 5

From: Bone marrow mesenchymal stem cells derived from juvenile macaques reversed ovarian ageing in elderly macaques

Fig. 5

Transcriptome sequencing of ovarian tissues. a Cluster plot showing the 1258 genes differentially expression. b 3D-PCA analysis of ageing-related genes, light green represents the young control group, purple represents the elderly model group, and dark blue represents the elderly treatment group. c ClueGO analysis functional enrichment of 1258 genes. d Trajectory analysis the ovarian expression characteristics of 415 upregulated genes with age and BMMSC treatment, and the GO enrichment. e Trajectory analysis of the ovarian expression characteristics of 843 downregulated genes with age and BMMSC treatment, and the GO enrichment. f Cytohub screened the top20 PPI. g PPI top 20 gene function and pathway

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