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Fig. 5 | Stem Cell Research & Therapy

Fig. 5

From: Therapeutic potential of human umbilical cord mesenchymal stem cells on aortic atherosclerotic plaque in a high-fat diet rabbit model

Fig. 5

Oil Red O Staining and detection of apoptosis and proliferation in the aorta. A Oil red O staining of the aorta; the percentage area of aorta lipid plaque in the model group was significantly larger than that in UCSCs and normal group. B HE results show there was different degree of lipid deposit and thickened intima wall in the model group. Apoptosis (TUNEL) of arterial cells decreased, proliferation (ki67) increased, and aortic EC antigen (CD31) expression increased in the UCSCs group. The last column is a representative display showing that most areas of the aorta did not produce plaques in the treatment group, bar = 100 μm. n = 8 in each group. *P < 0.05, **P < 0.01, compared with model group

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