Fig. 6

Treatment with 24-h educated LPS-EEMos treats hematopoietic ARS when infused 24 h post-radiation exposure. On day 0, NSG mice received 4 Gy of lethal radiation followed by an i.v. treatment either 24 h later with PBS (vehicle control) or 1 × 10⁷ LPS-EEMos, or 48 h later with 1 × 10⁷ LPS-EEMos. A Survival curve of treated mice after radiation. B Mean clinical scores (percent weight loss, posture, activity, and fur texture) compared to PBS controls. C Mean percent weight change compared with PBS controls. The final mean percent weight change and clinical score for a given animal were carried over after death to allow for comparison by Kruskal-Wallis with a Dunn post-test between groups at a given time point. Results pooled from two separate experiments, with 4 to 8 mice/group, *p ≤ 0.05