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Table 3 CBCs from lethally irradiated mice treated with LPS-EEMos followed by IL-6R blockade

From: Exosomes from primed MSCs can educate monocytes as a cellular therapy for hematopoietic acute radiation syndrome

Group

Day post rad

RBC (M/ul)

WBC (K/ul)

Neutrophils (K/ul)

Lymphocytes (K/ul)

Monocytes

(K/ul)

Platelets (K/ul)

Platelet volume (fL)

LPS-EEMos

40

8.9

2.14

1.33

0.51

0.24

630

5.1

LPS-EEMos + anti-IL6R

40

5.1*

0.94*

0.36**

0.38

0.19

425

5.2

LPS-EEMos + isotype control

40

8.9

2.6

1.71

0.54

0.30

480

4.9

  1. *P</= 0.05. **P</=0.005 as compared to untreated LPS-EEMos