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Fig. 6 | Stem Cell Research & Therapy

Fig. 6

From: A NOTCH1/LSD1/BMP2 co-regulatory network mediated by miR-137 negatively regulates osteogenesis of human adipose-derived stem cells

Fig. 6

LSD1 or BMP2 knockdown influences NOTCH1/LSD1/BMP2 signaling network. a Relative expression analyses of LSD1, NOTCH1, and HES1 by qRT-PCR in transfected hASCs on 3 days, 7 days, and 14 days. b, c Western blotting (b) and band intensity analyses (c) of LSD1, NOTCH1, and HES1 in transfected hASCs on 7 days. d Relative expression analyses of BMP2, NOTCH1, HES1, and LSD1 by qRT-PCR in transfected hASCs on 3 days, 7 days, and 14 days. e, f Western blotting (e) and band intensity analyses (f) of BMP2, NOTCH1, HES1, and LSD1 in transfected hASCs on 7 days. Data are shown as mean ± SD of three independent experiments performed in triplicate. *p < 0.05, **p < 0.01, ***p < 0.001 versus respective NC group

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Stem Cell Research & Therapy

ISSN: 1757-6512