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Table 1 Clinical characteristics and outcome of patients

From: Unresponsive thin endometrium caused by Asherman syndrome treated with umbilical cord mesenchymal stem cells on collagen scaffolds: a pilot study

Patient Age (years) Symptoms Etiology of AS (times) Prior repair attempts Score of AS at 1st HSA Previous treatment received ET (pre-/post-therapy mm) Pregnancy outcome
P1 39 Infertility (3 years)
Hypomenorrhea
5 D&C 3 HSA AS Stage II Estrogen/Aspirin/Heparin/GH/Sildenafil/traditional Chinese medicine 5.5/7.1 2 FET and implantation failure
P2 33 Infertility (3 years)
Hypomenorrhea
1 D&C 3 HSA AS Stage III Estrogen/Aspirin/Heparin/Sildenafil 3/6.1 1 FET and implantation failure
P3 30 Infertility (4 years)
Hypomenorrhea
1 HSP
1 D&C
5 HSA AS Stage IV Estrogen/Aspirin/Heparin/GH /Sildenafil/G-CSF/GM-CSF/traditional Chinese medicine 5.1/6.6 3 FET and implantation failure
P4 37 Infertility (3 years) 6 D&C 2 HSA AS Stage IV Estrogen/Aspirin/Heparin/GH /G-CSF 5.1/5.9 1 FET and implantation failure
P5 34 Infertility (3 years)
Hypomenorrhea
2 D&C 2 HSA AS Stage II Estrogen/Aspirin/traditional Chinese medicine 5.2/5.8 1 FET 4 months post-treatment and cesarean section at 35 + 5 weeks, girl,1950 g
P6 34 Infertility (6 years)
Hypomenorrhea
2 D&C 5 HSA AS Stage IV Estrogen/Aspirin/Heparin/GH/Sildenafil 2.3/6.1 1 FET and implantation failure
P7 35 Infertility (4 years)
Hypomenorrhea
4 D&C 4 HSA AS Stage II Estrogen/Aspirin/Heparin/GH/G-CSF 5.1/6.4 2 FET and implantation failure
P8 35 Infertility (4 years)
Hypomenorrhea
1 D&C 3 HSA AS Stage III Estrogen/Aspirin/Heparin 4.5/6.6 1 FET 2 months post-treatment and abortion at 25+ weeks
P9 39 Infertility (6 years)
Hypomenorrhea
1 D&C 3 HSA AS Stage IV Estrogen/Aspirin/Heparin/GH/Sildenafil 3.7/5 2 FET and implantation failure
P10 30 Infertility (1 year)
Hypomenorrhea
4 D&C 2 HSA AS Stage III Estrogen/Aspirin/Heparin/Sildenafil 3.5/4.5 Spontaneous pregnancy 9 months post-treatment and natural labor at 39 weeks, boy, 2600 g
P11 37 Infertility (3 years)
Hypomenorrhea
3 D&C 2 HSA AS Stage IV Estrogen/Aspirin/Heparin 4.5/- Did not measure ET after treatment and no FET
P12 36 Infertility (4 years)
Hypomenorrhea
3 D&C 3 HSA AS Stage III Estrogen/Aspirin 3.4/5.8 1 FET and implantation failure
P13 31 Infertility (5 years)
Hypomenorrhea
2 D&C 3 HSA AS Stage IV Estrogen/Aspirin/Heparin/Sildenafil/G-CSF 4.9/6.4 2 FET and implantation failure
P14 33 Infertility (5 years)
Hypomenorrhea
8 D&C 4 HSA AS Stage III Estrogen/Aspirin/Heparin/Sildenafil 4.2/5.9 2 FET and implantation failure
P15 26 Infertility (5 years)
Amenorrhea
2 D&C 5 HSA AS Stage VA Estrogen/Aspirin/Heparin/Sildenafil 2.5/4.7 1 FET and implantation failure
P16 37 Infertility (2 years)
Hypomenorrhea
1 D&C 3 HSA AS Stage IV Estrogen/Aspirin/Heparin 3.5/- Withdrew
P17 32 Infertility (1 years)
Amenorrhea
1 D&C 3 HSA AS Stage Va Estrogen/Aspirin/Heparin 4.4/6.3 1 FET 3 months post-treatment and natural labor at 40 + 1 weeks, girl, 2900 g
P18 39 Infertility (12 years) 1 D&C 3 HSA AS Stage IV Estrogen/Aspirin/Heparin/G-CSF 3/4.7 1 FET and implantation failure
  1. P, patient; D&C, dilatation and curettage; HSP, hysteroscopic polypectomy; HSA, hysteroscopic adhesiolysis; AS, Asherman, syndrome; ET, endometrial thickness; GH, growth hormone; G-CSF, granulocyte colony-stimulating factor; FET, frozen–thawed embryo transfer