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Fig. 6 | Stem Cell Research & Therapy

Fig. 6

From: miR-20a-5p contributes to osteogenic differentiation of human dental pulp stem cells by regulating BAMBI and activating the phosphorylation of Smad5 and p38

Fig. 6

miR-20a-5p/BAMBI axis-regulated osteogenesis via phosphorylation of Smad5 and p38. A Western blot analyses of pSmad5, Smad5, p-p38, p38, and the internal control GAPDH in miR-NC, miR-20a-5p, anti-miR-20a-5p, si-BAMBI, and si-NC groups. B The protein levels of pSmad5, Smad5, p-p38, p38, and GAPDH in miR-NC, miR-20a-5p, anti-miR-20a-5p, si-BAMBI, and si-NC groups. C Schematic model showed that miR-20-5p promotes osteogenic differentiation by the BAMBI-mediated activation of p-Smad5 and p-p38 pathways. **p <0.01 compared with the si-NC/miR-NC groups

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