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Fig. 2 | Stem Cell Research & Therapy

Fig. 2

From: Pretreatment of cardiac progenitor cells with bradykinin attenuates H2O2-induced cell apoptosis and improves cardiac function in rats by regulating autophagy

Fig. 2

BK regulated the H2O2-induced apoptosis- and autophagy-related proteins. Representative of image and quantitative analysis of western blot assay detected apoptosis-related proteins, pAkt (A), Bax (B), Bcl-2 (C), and cleaved-caspase 3 (D) in hCPCs induced by H2O2 and treatment with BK (1, 3, 10 nM). Representative of image and quantitative analysis of western blot assay detected autophagy-related proteins, LC3II/I (E), Beclin 1 (F), ATG5 (G), and P62 (H) in hCPCs induced by H2O2 and treatment with BK (1, 3, 10 nM). (Data are shown as mean ± SEM, n = 5, *P < 0.05, **P < 0.01 VS. Control; #P < 0.05, ##P < 0.01 VS. H2O2)

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