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Fig. 4 | Stem Cell Research & Therapy

Fig. 4

From: Pretreatment of cardiac progenitor cells with bradykinin attenuates H2O2-induced cell apoptosis and improves cardiac function in rats by regulating autophagy

Fig. 4

BK-treated hCPCs improved left ventricular function in MI rats. A Representative image of the echocardiography detected at 6 weeks after MI. Data analysis of the left ventricular fractional shorting (LVFS) (B), ejection fraction (LVEF) (C), left ventricular internal diameter at end-systole (LVIDs) (D), and left ventricular internal diameter at end-diastole (LVIDd) (E) were showed in the sham group (Sham), MI rats treated with the PBS group (PBS), MI rats transplanted with the hCPC-negative cell group (hCPC- cells), MI rats transplanted with the hCPC group (hCPCs), MI rats transplanted with the BK-treated hCPC group (BK-hCPCs), and MI rats transplanted with the 3-MA-treated hCPC group (3-MA-hCPCs). (Data are shown as mean ± SEM, n = 6, **P < 0.01 VS. Sham; #P < 0.05, ##P < 0.01 VS. MI; &P < 0.05 VS. hCPCs-MI)

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Stem Cell Research & Therapy

ISSN: 1757-6512