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Fig. 1 | Stem Cell Research & Therapy

Fig. 1

From: Extracellular vesicles derived from LPS-preconditioned human synovial mesenchymal stem cells inhibit extracellular matrix degradation and prevent osteoarthritis of the knee in a mouse model

Fig. 1

Identification of human SMSCs and extracellular vesicles. a SMSCs exhibited a spindle-like morphology. b SMSCs showed multidirectional differentiation potential of osteogenesis, adipogenesis, and chondrogenesis. c Characteristic cell surface markers of SMSCs were analyzed by flow cytometry. d EVs and LPS-pre EVs observed through TEM. e Particle size distribution of EVs and LPS-pre EVs analyzed by NanoSight. f extracellular vesicles markers (CD9, CD63, Alix, TSG101) analyzed by western blot. g Chondrocyte internalization of EVs and LPS-pre EVs as observed under fluorescence microscope

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