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Fig. 7 | Stem Cell Research & Therapy

Fig. 7

From: Impact of human adipose tissue-derived stem cells on dermatofibrosarcoma protuberans cells in an indirect co-culture: an in vitro study

Fig. 7

Induction of angiogenesis. A Representative images of HUVECs forming tubes upon treatment with different CMs. Scale bars=500 μm. B Representative images of HUVECs forming tubes upon treatment with different CMs with auxiliary lines. Scale bars=500 μm. Nodes: Red (#ff1303), Junction: Blue (#0035ff), Master Junction: OrangeRed (#ff2d00), Mesh: Deepskyblue (#06adfd), Segment: Magenta (#f00efc), Master Segment: Gold (#ffd300), Branch: LimeGreen (#23e500), Twig: Cyan (#19e7fb), Isolated twig: Aqua (#00f7fa), Extremity: Crimson (#f70133), Extremity edge: Yellow (#f7eb00), Isolated element: Mediumblue (#0005fe). C Number of meshes, D total tube length, and E total branch length of HUVECs induced by ADSC-CM, DFSP-CM, and co-cultured DFSP/ADSC-CM at 4 h, respectively. **p<0.01 indicates significant differences between the co-cultured DFSP/ADSC-CM and control groups (ADSC-CM or DFSP-CM) in at least three independent experiments. ADSCs, adipose tissue-derived stem cells; CM, conditioned medium; DFSP, dermatofibrosarcoma protuberans; DMEM, Dulbecco’s modified Eagle’s medium; HUVECs, human umbilical vein endothelial cells

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