Clinical and imaging outcomes after intrathecal injection of umbilical cord tissue mesenchymal stem cells in cerebral palsy: a randomized double-blind sham-controlled clinical trial

Table 1 Baseline demographic characteristics

Demographics	Control n=36	UCT-MSC n=36	P value
Gender N (%)
Female	17 (47.2)	15 (41.7)	0.339
Male	19 (52.8)	21 (58.3)
Age (months)
Mean (SD)	102.5 (29.9)	101.7 (32.1)	0.186
Weight (kg)
Mean (SD)	17.3 (7.2)	17.5 (8.5)	0.30
Type of cerebral palsy
Spastic quadriplegia	32 (88.9)	30 (83.3)	0.491
Spastic diplegia	4 (11.1)	6 (16.7)
GMFCS, N
II/III/IV/V	4/4/11/17	5/7/10/14	0.876
GMFM-66 score
Mean (SD)	66.3 (50.7)	70.2 (45.0)	0.769
Modified Ashworth scale
Mean (SD)	3.16 (0.97)	2.91 (1.12)	0.215
PEDI-Self-care
Mean (SD)	21.77 (16.15)	24.37 (17.09)	0.518
PEDI-Mobility
Mean (SD)	16.07 (14.01)	17.53 (11.98)	0.682
PEDI-Social function
Mean (SD)	26.63 (18.76)	32.08 (20.33)	0.243
CP-QOL
Mean (SD)	369.8 (56.2)	364.4 (46.1)	0.644
FA corticospinal tract
Mean (SD)	0.433 (0.63)	0.448 (0.40)	0.371
FA posterior thalamic radiate
Mean (SD)	0.341 (0.40)	0.354 (0.32)	0.364
MD corticospinal tract^*
Mean (SD) ×10³	0.967 (0.07)	0.972 (0.06)	0.271
MD posterior thalamic^* radiate
Mean (SD) ×10³	1.060 (0.12)	1.067 (0.07)	0.943

SD standard deviation, GMFCS growth motor classification system, GMFM growth motor function measurement, PEDI pediatric evaluation of disability inventory, CP-QOL cerebral palsy quality of life child, FA fractional anisotropy, MD mean diffusivity
*The means (SD) should be divided by 1000

ISSN: 1757-6512