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Table 2 The GMFM-66 and MAS mean difference within-groups (from baseline) and the difference between groups

From: Clinical and imaging outcomes after intrathecal injection of umbilical cord tissue mesenchymal stem cells in cerebral palsy: a randomized double-blind sham-controlled clinical trial

Outcomes

Test of within-group (mean change from effects of baseline)

Test of between-groups effects (mean change from the control group)

Control

MSC

MSC vs control

Mean [95% CI]

Mean [95% CI]

β

95% CI

P.v

Cohen’s d [95% CI]

GMFM-66

 T1

−0.02 [−4.79, 4.75]

4.47 [−0.73, 9.68]

4.59

[−1.16, 10.35]

0.11

0.45 [−0.01, 0.92]

 T2

2.03 [−2.97, 7.04]

6.85 [1.49, 12.20]

4.81

[−0.23, 9.86]

0.062

0.48 [−0.01, 0.93]

 T3

−0.58 [−5.32, 4.15]

11.27 [6.01, 16.53]

11.90

[5.42, 18.37]

<0.001

1.11 [0.54, 1.67]

 T4

1.23 [−3.33, 5.80]

10.65 [5.39, 15.91]

8.07

[1.62, 14.52]

0.002

0.92 [0.34, 1.48]

MAS

 T1

−0.53 [−0.87, −0.18]

−0.94 [−1.24, −0.63]

−0.41

[−0.87, 0.04]

0.074

0.22 [−0.31, 0.75]

 T2

−0.66 [−0.99, −0.34]

−1.0 [−1.29, −0.70]

−0.33

[−0.77, 0.10]

0.132

0.11 [−0.37, 0.60]

 T3

−0.69 [−1.03, −0.35]

−1.26 [−1.56, −0.95]

−0.56

[−1.01, −0.11]

0.014

0.37 [0.14, 0.89]

 T4

−0.28 [−0.62, 0.05]

−1.0 [−1.31, −0.69]

−0.72

[−1.18, −0.26]

0.002

0.76 [0.20, 1.31]

  1. GMFM-66 gross motor function measure-66, MAS Modified Ashworth scale, T1 1-month data collection, T2 3-month data collection, T3 6-month data collection, T4 1-year data collection