Outcome | UCT-MSC (n=36) | control (n=36) |
---|---|---|
Fractional anisotropy | ||
Corticospinal tract | Â | Â |
12 months mean (SD) | 0.48 (0.04) | 0.42 (0.06) |
Mean changes from baseline (95% CI) | 0.032 (0.02 to 0.03) | −0.007 (−0.010 to −0.002) |
Difference vs control (95% CI) | 0.055 (0.02 to 0.08) | – |
Cohen’s d (95%CI) | 0.81 (0.36 to 1.26) | – |
Posterior thalamic radiate | Â | Â |
12 months mean (SD) | 0.37 (0.03) | 0.32 (0.04) |
Mean changes from baseline (95% CI) | 0.024 (0.020 to 0.028) | −0.020 (−0.02 to −0.01) |
Difference vs control (95% CI) | 0.059 (0.3 to 0.8) | – |
Cohen’s d (95%CI) | 1.04 (0.68 to 1.41) | – |
Mean diffusivity (×103)* | ||
Corticospinal tract | Â | Â |
12 months mean (SD) | 0.93 (0.05) | 1.00 (0.12) |
Mean changes from baseline (95% CI) | −0.035 (−0.04 to −0.02) | 0.040 (0.02 to 0.05) |
Difference vs control (95% CI) | −0.07 (−0.11 to −0.02) | – |
Cohen’s d (95%CI) | 0.77 (0.26 to 1.28) | – |
Posterior thalamic radiate | Â | Â |
12 months mean (SD) | 1.02 (0.07) | 1.09 (0.19) |
Mean changes from baseline (95% CI) | −0.045 (−0.05 to −0.03) | 0.033 (0.01 to 0.05) |
Difference vs control (95% CI) | −0.07 (−0.15 to −0.003) | – |
Cohen’s d (95%CI) | 0.55 (0.01 to 1.11) | – |